CDMO services

Contract Development and Manufacturing (CD/CM) Services

At Provis Biolabs, we offer comprehensive CDMO services for Bio-APIs, recombinant bioreagents and therapeutic peptides. Our state-of-the-art facilities, expert team and commitment to quality enable us to support clients from early-stage development to commercial-scale production.

Infrastructure

  •  State-of-the-Art Labs: Equipped with cutting-edge technology to enable efficient process development and production

Quality and Compliance

  • cGMP Regulations: Adherence to current Good Manufacturing Practices ensures product quality and safety
  • GLP Compliance: Good Laboratory Practices guarantee data integrity and reproducibility

Comprehensive Support

  • Gene-to-Product: Seamless support from gene cloning to final product formulation
  • Cloning to Formulation: Expertise in all stages of product development
  • Fermentation Optimization: Maximizing yield and efficiency through optimized fermentation conditions
  • Downstream Processing: Development and optimization of product purification processes

Flexible Scale-Up Capabilities

  • Lab Scale Runs: Up to 300L for early-stage development and small-scale production
  • Scale-up Capabilities: Suitable for both GMP and non-GMP production
  • Pilot Plant Access: Bridging the gap between lab-scale and industrial-scale production
  • Industrial Scale Runs: Large-scale production for commercial applications

Sustainable and Cost-Effective

  • Cost-Effective Solutions: Efficient processes and optimized resources minimize costs
  • Sustainability: Environmentally responsible practices ensure a reduced ecological footprint

Partner with Us

Rely on Provis Biolabs for your CD/CM needs. Contact us to discuss your project requirements and learn more about our services.

CDMO services

Provis Biolabs offers comprehensive Contract Development and Manufacturing Organization (CDMO) services with robust capabilities in microbial and bacterial production. Our expertise spans various product categories, ensuring high-quality outputs for diverse applications.

Recombinant Protein Expression, Process Development, cGMP Manufacturing, Custom Enzyme Development, Biocatalytic Processes.

Research & Development

  • State-of-the-art labs
  • Dedicated units for proteins, enzymes, and high-yield antibiotic strains.
  • Adherence to cGMP regulations
  • GLP compliance

Development Phase

  • Gene-to-product support.
  • Cloning to formulation.
  • Fermentation optimization
  • Development of downstream processing and product purification
  • Lab scale runs (Up to 300L)

Scale-Up & Commercial Manufacturing

  • Scale-up capabilities suitable for both GMP and non-GMP.
  • Pilot Plant Access
  • Industrial scale runs for large scale production
  • Cost-Effective Sustainability

Upstream Process

  • Strain and Cell line Development
  • Process Proof of Concept
  • Media & Process Development 
     Screening of medium components
     Design of experiments (DoE)
     Optimization of scale-up parameters
  • Fermentation and Scale Up

Facility Overview & Equipment

Current Setup

Suitable for Bacterial and Yeast expression systems

300KL Fermentation capacity

Cell separation, Filtration and product recovery

Downstream processing and Purification

Formulation, Freeze-drying/Spray drying and
Lyophilization

In-process quality control and batch release testing

Planned Expansion

Suitable for Bacterial and Yeast expression systems

2 million liters Fermentation capacity

Cell separation, Filtration and product recovery

Downstream processing and Purification

Formulation, Freeze-drying/Spray drying and
Lyophilization

In-process quality control and batch release testing

Future Focus on Mammalian Cell Culture, diversifying our production capabilities.